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DILANTIN‌-125® (phenytoin) Contraindications

4 CONTRAINDICATIONS

DILANTIN is contraindicated in patients with:

  • A history of hypersensitivity to phenytoin, its inactive ingredients, or other hydantoins [see Warnings and Precautions (5.5)]. Reactions have included angioedema.
  • A history of prior acute hepatotoxicity attributable to phenytoin [see Warnings and Precautions (5.8)].
  • Coadministration with delavirdine because of the potential for loss of virologic response and possible resistance to delavirdine or to the class of non-nucleoside reverse transcriptase inhibitors.
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